![]() But either way its worth a shot if you aren't already using them.Ĭaffeine (pre-workout) and during the day. Perhaps it helped some metabolic problem I was experiencing. I found it much easier to gain muscle and strength when I added Methylene Blue and later Thyroid in to my supplement regimen. Switch to casein for your shakes if you need shakes. I now take more casein protein and ditched whey so this probably wouldn't be needed. I never got up specifically to drink them but if I woke up at night to piss (usually did) then I would have a shake. How desperate are you to gain muscle, because this one sucks!?! Again I managed to increase my weight by roughly 2kgs in 2 weeks by adding a shake containing 30g protein. I also noticed a small amount of fat loss too. I gained 2kgs in 2 weeks doing this alone the first time I tried. At least 5g of leucine (or BCAA containing this amount) with every meal/snack. The 5- androstene-3-&?, 17-$3-diol, and 4-androstene-3,17-dione did not bring about any effect on the serum protein fractions.Ĭlick to expand.First off let me give you a few "non hormonal" things I have used to great success that you may or may not have tried. The same increase in albumin and a globulin was obtained with methyl testosterone, adrenosterone, androstane-3,17-dione, and pregnenolone, while a corresponding decrease was noticed in y globulin. Most of the steroids brought about an increase in the total protein content of the serum (Tables 1 & 2). ".The steroids showed no parallelism in their specific activity in bringing about the changes in serum protein concentrations. In the present study, the increase in the total protein content of the serum is taken as an index of anabolic potency of the steroid." Nowakowski, 1961) showed that the treatment of myopathies patients with 19-nortestosterone decanoate for 5- 6 months resulted in a significant increase in calcium and total protein content of the serum, but the changes in different protein fractions were not found to be statistically significant. ".The blood chemistry analysis of Hantschman and Mertens (unpublished data quoted by H. Levator ani muscle responds to both androgenic and anabolic components of the steroid (Edgren, 1963)." ".However, Nimni and Geiger (1957) concluded that the hormone-induced growth of the levator ani muscle is not an appropriate index for determining the anabolic effects of steroid compounds. Little work has been done in regard to the effect of the anabolic steroids on the serum protein concentrations, and no such information is available." The anabolic potency of a steroid could be assayed by measuring urinary nitrogen retention (Henderson and Weinberg, 1951 Potts ‘et al., 1960 Stucki et al., 1962 Arnold et al., 1963), myotrophic activity (Eisenberg et al., 1949 Kochakian and Tillotson, 1956 Dorfman and Dorfman, 1963 Kincl and Dorfman, 1964), renotrophic effect (Kochakian, 1947 Dorfman and Shipley, 1956)) erythropoiesis (Nathan and Frank, 1965), and other miscellaneous effects such as calcium and phosphorus metabolism and increase in body growth (Kochakian. ![]() The effect of certain steroids on the serum protein concentrations of the lizard, Uromastix hardwickii Gray In experiment 2 a similar range of doses of both steroids was given to the rats 1 h before the first retention test. ![]() ".In the first experiment in that study a range of doses of two anabolic steroids, pregnenolone sulfate and ethylestrenol, were given s.c. Non-linear effects in the retention of an avoidance task induced by anabolic steroids. The combination of anti-catabolic effects and promotion of protein synthesis (anywhere in the body) is a much more reliable measure of true anabolism, and pregnenolone (just as the well known AAS) satisfies those criteria quite well. So, it appears that focusing solely on muscle growth promoting properties of steroids is not an adequate indication of their anabolism. ![]() While pregnenolone was not as potent as testosterone, it still displayed clear anabolic effects as measured by blood protein concentration, brain trophic effects, and (in older studies) abolishing the nitrogen loss of catabolic states. However, older studies referred to pregnenolone as an anabolic steroid and some of them examined its anabolic effects. I posted a few studies showing pregnenolone has anti-cortisol and anti-estrogen effects, which make it anti-catabolic by definition. ![]()
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